Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (C-Term) Peptide
LTB
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN2185599
Aperçu rapide pour Lymphotoxin beta (TNF Superfamily, Member 3) (LTB) (C-Term) Peptide (ABIN2185599)
Antigène
LTB
(Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- PELLLEGAET VTPVLDPARR QGYGPLWYTS VGFGGLVQLR RGERVYVNIS
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-LTB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LTB (Lymphotoxin beta (TNF Superfamily, Member 3) (LTB))
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Sujet
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Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 Molecule alpha/2 Molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
Protein Size: 244 -
Poids moléculaire
- 26 kDa
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ID gène
- 4050
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UniProt
- Q06643
Antigène
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